
Sperm Extraction
Severe male factor infertility often precludes treatment with
intrauterine insemination (IUI). When greatly decreased sperm
count (severe oligospermia) is diagnosed in the ejaculate,
intracytoplasmic sperm injection (ICSI) is
required to achieve fertilization in the laboratory. However, when
no sperm is identified in the ejaculate (azoospermia), alternative
methods other than ejaculation must be employed in order to
harvest sperm for use with ICSI. The type of sperm extraction
procedure used depends on the etiology for azoospermia. In males
with obstructive azoospermia, secondary to an absence or
obstruction of the ejaculatory ducts (i.e. congenital bilateral
absence of the vas deferens, vasectomy...), percutaneous epididymal
sperm aspiration (PESA) or microsurgical epididymal sperm
aspiration (MESA) may be used to isolate sperm directly from the
epididymis (collecting tubule adjacent to each testis) for use
with ICSI. When non-obstructive azoospermia is diagnosed
(diminished sperm production within the testes), a testicular
sperm extraction (TESE) may be performed. With TESE small
fragments of testicular tissue are removed and sperm are isolated
by careful dissection for use with ICSI. Sperm extraction
procedures are usually performed on the day of egg retrieval in
order to obtain fresh sperm for fertilization with ICSI. If enough
sperm is obtained, some sperm may be frozen for later use so that
additional extraction procedures may be avoided. All sperm
extraction procedures are performed by a urologist, usually under local anesthesia.
The California Center for Reproductive Health employs the services of highly-qualified, board certified urologists who perform all sperm extraction procedures with utmost care directly on our premises.